PP 12. Geriatric Nutritional Risk Index For Esophageal Cancer

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I. Yamana, S. Takeno, R. Shibata, H. Shiwaku, K. Maki, T. Hashimoto, T. Shiraishi, J. Iwasaki, Y. Yamashita

19:16 - 19:22h at Margrit Room

Categories: Gastrointestinal Surgery, Poster Session

Session: Poster (P1) - Gastrointestinal Surgery

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Background
The Geriatric Nutritional Risk Index (GNRI) is a new index recently introduced for predicting risk of nutritional-related complications. Mainly, GNRI has been reported as a simple and accurate tool to assess nutritional status and prognosis of hemodialysis patients. GNRI has never been reported relating to the patients with gastrointestinal cancer. Our object was to examine the association between GNRI and short term outcomes especially postoperative complication in the patients with esophageal cancer performed esophagectomy and gastric tube reconstruction.

Material and Methods
The present study enrolled 152 consecutive patients with esophageal cancer performed esophagectomy and gastric tube reconstruction. GNRI on admission was calculated as follows; (1.489×albumin, g/l)+(41.7×present/ideal body weight). Characteristics and short term outcomes were compared between 4 groups: major nutrition related risk (GNRI: <82), moderate nutrition related risk (GNRI: 82 to <92), low nutrition related risk (GNRI: 92 to <98), and no nutrition-related risk (GNRI: ≧98), respectively.

Result
Mean age of the 152 patients was 64.4±9.2 (range: 39-84). Pathological stage, respiratory complication, and open thoracotomy cases were correlated positively to GNRI score, respectively (p=0.0051, p=0.0051, p=0.0083). Multivariate analysis demonstrated that major nutrition related risk (GNRI: <82) was independently significant factors for respiratory complication (Hazard ratio: 2.07, 95% confidence interval : 1.088-21.85, p=0.038 ).

Conclusion
The simple method of GNRI is considered to be a clinically useful marker for the assessment of nutritional status and predictor of respiratory complication in the patients with esophageal cancer performed esophagectomy and gastric tube reconstruction.