PP 43. Thrombotic Complications of Chemotherapy and Breast Reconstruction


K. Richards, C. Malata, P. Forouhi, A Johnston

19:22 - 19:28h at Margrit Room

Categories: Abdominal Wall and Hernia, Plastic and Reconstructive Surgery, Poster Session

Session: Poster (P3) - Abdominal Wall & Hernia / Plastic & Reconstructive Surgery


Background
Thrombotic complications arising during the treatment of breast cancer can impact the breast reconstruction pathway. We set out to review the details of cases of thromboembolism occurring during neoadjuvant chemotherapy and peri-operatively to study the impact of the event and its management on subsequent breast reconstruction.

Material and Methods
We retrospectively reviewed the medical records of seven patients who had experienced a thrombotic event during their treatment of breast cancer between 2008 and 2012, who then proceeded to breast reconstruction. We recorded size and grade of tumour, neoadjuvant chemotherapeutic regimen, details of port insertion, planned reconstruction, thrombotic event and its management and the surgery performed and outcome.

Result
All patients received chemotherapy via central venous access and went on to present with local symptomatic thrombosis. They were managed with anticoagulant regimens at the time of mastectomy and reconstruction, which were unique for each patient. The results revealed delays to surgery and modifications to planned reconstruction.

Conclusion
An awareness of the effects of thrombotic events in this patient group is important in terms of developing an understanding of its impact on the performance of reconstruction, on the management of anticoagulation peri-operatively and on monitoring for post-operative complications.