PP 54. Simultaneous Occurrence of Clear Cell Hepatocellular Carcinoma and Clear Cell Renal Carcinoma. Management and Review of The Literature.
I. Koukoutsis, K. Gouzis, I. Matzoukas, A Trellopoulos, G. Karavitis, N. Salemis, E. Lagoudianakis
19:04 - 19:10h
at Lanchid Room
Categories: Poster Session , Surgical Oncology
Session: Poster (P4) - Surgical Oncology
Background
The clear cell variant of hepatocellular carcinoma is a rare clinical entity comprising less than 10% of the cases of hepatocellular carcinoma. We present an extremely rare case of simultaneous resection of clear cell hepatocellular carcinoma and clear cell renal carcinoma and review the relevant literature.
Material and Methods
A 69 -year– old Caucasian male presented with retractable hiccup. During investigations, the computed tomography (CT) and abdominal MRI revealed a 3cm hypovascularised fatty infiltrated liver lesion in attachment with the right posterior sector portal branch and a right kidney solid hypervascular mass highly suspicious for malignancy.
Result
A CT-guided FNB of the liver lesion was performed to exclude the possibility of liver metastasis from the renal tumor. The liver tumor biopsy revealed hepatocellular carcinoma of predominantly clear cell type. At laparotomy, resection of VI, most of VII and part of V hepatic segments was performed along with right nephrectomy. The postoperative period was complicated by ascites (500- 700ml/day for ten days-no diuretics used). The final histology report revealed clear cell hepatocellular carcinoma and renal clear cell carcinoma with tumor-free surgical margins. No adjuvant systemic treatment was administered. The patient is well and asymptomatic 2 months after surgery.
Conclusion
The simultaneous occurrence of primary clear cell hepatocellular carcinoma and clear cell renal carcinoma is an extremely rare clinical entity. Simultaneous resection can be performed after a thorough preoperative workup. Accurate preoperative evaluation of the liver lesion is mandatory in order to exclude the possibility of a liver metastasis from the renal tumor.
