PP 59. Postoperative Nutritional Status Following Total Pancreatectomy Compared with Pancreaticoduodenectomy

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J. Watanabe, T. Mizumoto, T. Takebayashi, K. Tamura, H. Sato, E. Ito, S. Kageyama, M. Hatano, H. Inoue, T. Izumi, A Takai, T. Tohyama, F. Kushihata, Y. Takada

19:34 - 19:40h at Lanchid Room

Categories: Poster Session , Surgical Oncology

Session: Poster (P4) - Surgical Oncology

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Background
Patients after total pancreatectomy (TP) are susceptible to metabolic nutritional disorder such as diarrhea and diabetes mellitus. However, patient life after TP has been improved by development of postoperative care and new insulin pharmaceutical. We evaluated long-term nutritional status of the patients after TP.

Material and Methods
We examined patients underwent total pancreatectomy (TP group) from 2008 to 2013 comparing with patients performed pancreaticoduodenectomy (PD group) in 2011. The observation period was 12 months after operation. We examined body weight change, HbA1c value, serum albumin (Alb) value, serum total cholesterol (T-chol) value, peripheral lymphocyte counts (TLC). In addition, we examined Controlling Nutritional Status (CONUT) value which was scored with serum Alb value, serum T-cho value and TLC.

Result
The Patients underwent TP were 7 (pancreatic carcinoma 5 cases, IPMN one case and P-NET one case). Four patients had recurrence, and 2 cases in them died. In the TP group, there was no difference in postoperative body weight change, nutritional status compared with PD group (15 cases). However, HbA1c value in TP group was higher in postoperative 3, 6, 12 months than it in PD group, and the TLC value in TP group was lower in postoperative 12 months than it in PD group. In addition, the CONUT value in TP group was higher than that in PD group in preoperation and postoperative 12 months.

Conclusion
Nutritional status after total pancreatectomy was approximately equal to pancreaticoduodenectomy. However, it was suggested that immunocompetence after total pancreatectomy was deteriorated in comparison with pancreaticoduodenectomy..