PP 73. Hepatic Vascular Anatomy of Rodents and Their Surgical Implications

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C. Sänger, A Schenk, L. Ole Schwen, Weiwei, F. Gremse, S. Zarfania, F. Kiessling, O. Dirsch, U. Dahmen

19:28 - 19:34h at Lanchid Room

Categories: Hepatobiliary and Pancreatic Surgery, Poster Session

Session: Poster (P5) - Hepatobiliary & Pancreatic Surgery

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Background
The need for precise experimental-surgical-procedures parallels the development of clinicalhepatobiliary- surgery rising.
The intra-hepatic vascular anatomy in rodents & its variations has not yet been described. We performed a detailed anatomical imaging study in rats & mice to allow for further refinement of experimental surgical approaches.

Material and Methods
15 LEWIS-rats & 15 C57Bl/6N-mice were subjected to imaging using CT-or MRI-technology. 3Dreconstruction was prepared for an analysis of the hepatic vascular anatomy.

Result
In rats the right-inferior-lobe was not only supplied by a single right- inferior-PV (4/15cases), but received additional blood supply through a branch of the right-superior-PV (11/15cases). This is surgically relevant when ligate the right-superior-PV prior to resection. The right-inferior-lobe can lead to atrophy & in case of simultaneous ligation of the corresponding branch of the hepatic-artery to necrosis of the right-inferior-lobe. In mice in 7/15cases the right-lobe is supplied by a right-PV stem, which divides into right-superior & right-inferior-PV. In 1/15cases, the right-superior & right-inferior-PV originate directly from the
main portal stem. In both species the distance between the right-superior- & right-median-HV was also variable. In case of a small distance, the piercing suture placed for resection of the right-median-lobe can damage the right-superior-HV & compromise its outflow.

Conclusion
Refinement of experimental hepatobiliary procedures in terms of resection or ligation of portal- &/or hepatic-vein branches requires knowledge of the intra-hepatic vascular anatomy.