PP 137. The Diagnostic Value of IMA and MPV in a Rat Model of Mesenteric Ischemia

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G. Cantilav, T. Oruç, T. Bilecik, B. Rafet Karakaş, H. Yaşar Ellidağ, N. Bülbüller

16:36 - 16:42h at Lanchid Room

Categories: Innovative Surgical Research, Novel Techniques and Product, Poster Session

Session: Poster II (P5) - Innovation / Education

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Background
Although less frequently observed compared to other abdominal causes, Acute Mesenteric Ischemia(AMI) is an abdominal vascular emergency that has high mortality rates(60-80%) often due to late diagnosis. This study aims to investigate the value of ischemia modified albumin and average trombosit volume on early diagnosis of mesenteric ischemia.

Material and Methods
For this experimantal research, we used three groups each consisting of 8 rats; 1st group: laparotomy is not done, 2nd group: laparotomy is done 3rd group: caused to develop mesenteric ischemia. Blood samples taken from both groups on 2nd hour for serum IMA and MPV measurements.

Result
Average MPV values were 10,9±0,6 for mesenteric ischemia group(Group C) which was reasonably higher (p<0,05) than Group B (7.0± 0,2) and Group A(6,6±0,3). IMA values were reasonably higher(p>0,05) in mesenteric ischemia group (Group C) with an average 274,5 ±17,5 than Group B(180,3± 6,3) and Group A (183,2± 2,3)

Conclusion
Even though the laboratory and imaging techniques showing rapip improvement, early diagnosis ofAMI is still very hard for a surgeon. Considering that late diagnosis is the main reason increasing  morbidity and mortality for patients with Acute Mesenteric İschemia, there is major need for markers particularly indicating pre-ischemia. In this study we obtained reasonable results showing high MPV and IMA values could be used as an indicator for early diagnosis of artery origined mesenteric ischemia.