PP 139. Evaluation of Two Different Barbed Sutures for End-To-End Jejunojejunal Anastomosis in Pigs

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M. Gandini, G. Giusto, S. Iussich, M. Tursi, G. Perona

16:48 - 16:54h at Lanchid Room

Categories: Innovative Surgical Research, Novel Techniques and Product, Poster Session

Session: Poster II (P5) - Innovation / Education

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Background
Barbed sutures are characterized by the presence of barbs cut into the body of the thread that allows knotless suturing. These sutures has proven effective in performing end-to-end anastomosis ex-vivo in dogs and horses but to date no experimental study evaluated the characteristics of such anastomoses in vivo. The aim of this study is to compare two different barbed suture materials for extramucosal end-toend jejuno-jejunal anastomosis in pigs.

Material and Methods
Three pigs were subjected to a total of 18 end-to-end jejuno-jejunal anastomosis with a continuousextramucosal pattern. In each animal two anastomoses were performed with Barbed Glycomer 631,  two with Barbed Polydioxanone and two with normal Glycomer 631. Construction time was measured and compared. Animals were euthanased 8 days after surgery. At necropsy adhesions, stenosis, leakage, presence of abscesses or granulomas at the anastomotic site were recorded.
Bursting pressure was measured for each anastomosis and compared. Samples were submitted for histopathology to evaluate inflammation and healing.

Result
Between barbed sutures the Barbed Polydioxanone was subjectively easier to handle. Construction time was significantly faster with barbed sutures. The presence and type of adhesions didn't differ between groups. There was no evidence of stenosis or leaking at anastomotic sites. Bursting pressure was higher with both barbed sutures. Histologically no difference could be detected in the grade of inflammation.

Conclusion
Barbed sutures can be effectively used for extramucosal anastomosis in pigs. They are comparable to Normal Glycomer 631 but could provide higher resistance with a shorter surgical time.